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Complex dynamics of hepatitis B virus resistance to adefovir

In patients with hepatitis B e antigen-negative chronic hepatitis B, adefovir dipivoxil administration selects variants bearing reverse transcriptase rtN236T and/or rtA181V/T substitutions in 29% of cases after 5 years. The aim of this work was to characterize the dynamics of adefovir-resistant vari...

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Autors principals: Pallier, Coralie, Rodriguez, Christophe, Brillet, Rozenn, Nordmann, Patrice, Hézode, Christophe, Pawlotsky, Jean-Michel
Format: Artigo
Idioma:Inglês
Publicat: Wiley 2009
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2956748/
https://ncbi.nlm.nih.gov/pubmed/19065672
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/hep.22634
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