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Analysis of Ribavirin Mutagenicity in Human Hepatitis C Virus Infection

The addition of ribavirin to alpha interferon therapy significantly increases response rates for patients with chronic hepatitis C virus (HCV) infection, but ribavirin's antiviral mechanisms are unknown. Ribavirin has been suggested to have mutagenic potential in vitro that would lead to “error...

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Detalhes bibliográficos
Main Authors: Chevaliez, Stéphane, Brillet, Rozenn, Lázaro, Ester, Hézode, Christophe, Pawlotsky, Jean-Michel
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2007
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1933365/
https://ncbi.nlm.nih.gov/pubmed/17494069
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00382-07
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