Deep Sequencing Reveals Mutagenic Effects of Ribavirin during Monotherapy of Hepatitis C Virus Genotype 1-Infected Patients

The preeminent mode of action of the broad-spectrum antiviral nucleoside ribavirin in the therapy of chronic hepatitis C is currently unresolved. Particularly under contest are possible mutagenic effects of ribavirin that may lead to viral extinction by lethal mutagenesis of the hepatitis C virus (H...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Hauptverfasser: Dietz, Julia, Schelhorn, Sven-Eric, Fitting, Daniel, Mihm, Ulrike, Susser, Simone, Welker, Martin-Walter, Füller, Caterina, Däumer, Martin, Teuber, Gerlinde, Wedemeyer, Heiner, Berg, Thomas, Lengauer, Thomas, Zeuzem, Stefan, Herrmann, Eva, Sarrazin, Christoph
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Microbiology 2013
Schlagworte:
Vaccines and Antiviral Agents
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3648094/
https://ncbi.nlm.nih.gov/pubmed/23536652
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.02778-12
Tags: Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!

Ähnliche Einträge