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Dynamics of Hepatitis B Virus Resistance to Lamivudine
Lamivudine was the first approved inhibitor of hepatitis B virus (HBV) reverse transcriptase (RT). Lamivudine resistance develops in 53% to 76% of patients after 3 years of treatment. We extensively characterized the dynamics of HBV quasispecies variant populations in four HBV-infected patients who...
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| Hauptverfasser: | , , , , , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
American Society for Microbiology
2006
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1346832/ https://ncbi.nlm.nih.gov/pubmed/16378967 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.80.2.643-653.2006 |
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