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Dynamics of Hepatitis B Virus Resistance to Lamivudine

Lamivudine was the first approved inhibitor of hepatitis B virus (HBV) reverse transcriptase (RT). Lamivudine resistance develops in 53% to 76% of patients after 3 years of treatment. We extensively characterized the dynamics of HBV quasispecies variant populations in four HBV-infected patients who...

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Bibliografiske detaljer
Main Authors: Pallier, Coralie, Castéra, Laurent, Soulier, Alexandre, Hézode, Christophe, Nordmann, Patrice, Dhumeaux, Daniel, Pawlotsky, Jean-Michel
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology 2006
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1346832/
https://ncbi.nlm.nih.gov/pubmed/16378967
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.80.2.643-653.2006
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