Development of PEGylated PLGA nanoparticle for controlled and sustained drug delivery in cystic fibrosis

BACKGROUND: The mutation in the cystic fibrosis transmembrane conductance regulator (CFTR) gene results in CF. The most common mutation, ΔF508-CFTR, is a temperature-sensitive, trafficking mutant with reduced chloride transport and exaggerated immune response. The ΔF508-CFTR is misfolded, ubiquitina...

Полное описание

Сохранить в:
Библиографические подробности
Главные авторы: Vij, Neeraj, Min, Taehong, Marasigan, Rhul, Belcher, Christopher N, Mazur, Steven, Ding, Hong, Yong, Ken-Tye, Roy, Indrajit
Формат: Artigo
Язык:Inglês
Опубликовано: BioMed Central 2010
Предметы:
Research
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC2954907/
https://ncbi.nlm.nih.gov/pubmed/20868490
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1477-3155-8-22
Метки: Добавить метку
Нет меток, Требуется 1-ая метка записи!

Схожие документы