Development of PEGylated PLGA nanoparticle for controlled and sustained drug delivery in cystic fibrosis

BACKGROUND: The mutation in the cystic fibrosis transmembrane conductance regulator (CFTR) gene results in CF. The most common mutation, ΔF508-CFTR, is a temperature-sensitive, trafficking mutant with reduced chloride transport and exaggerated immune response. The ΔF508-CFTR is misfolded, ubiquitina...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Main Authors: Vij, Neeraj, Min, Taehong, Marasigan, Rhul, Belcher, Christopher N, Mazur, Steven, Ding, Hong, Yong, Ken-Tye, Roy, Indrajit
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2010
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2954907/
https://ncbi.nlm.nih.gov/pubmed/20868490
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1477-3155-8-22
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados