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PEGylated PLGA nanoparticles for the improved delivery of doxorubicin

We hypothesize that the efficacy of doxorubicin can be maximized and dose-limiting cardiotoxicity minimized by controlled release from PEGylated nanoparticles. To test this hypothesis, a unique surface modification technique was used to create PEGylated PLGA nanoparticles encapsulating doxorubicin....

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Bibliografiske detaljer
Main Authors: Park, Jason, Fong, Peter M., Lu, Jing, Russell, Kerry S., Booth, Carmen J., Saltzman, W. Mark, Fahmy, Tarek M.
Format: Artigo
Sprog:Inglês
Udgivet: 2009
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2789916/
https://ncbi.nlm.nih.gov/pubmed/19341815
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.nano.2009.02.002
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