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In vivo distribution of surface-modified PLGA nanoparticles following intravaginal delivery

Intravaginal (ivag) delivery, which is a proven way to confer local protection against STD’s contracted via the reproductive tract, is complicated by the mucus gel barrier, the hormone cycle, and the harsh mucosal environment, which leads to low residence-time for administered agents. Polymer delive...

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Bibliografiske detaljer
Main Authors: Cu, Yen, Booth, Carmen J., Saltzman, W. Mark
Format: Artigo
Sprog:Inglês
Udgivet: 2011
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3220785/
https://ncbi.nlm.nih.gov/pubmed/21763739
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jconrel.2011.06.036
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