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Low Molecular Weight Chitosan-Coated PLGA Nanoparticles for Pulmonary Delivery of Tobramycin for Cystic Fibrosis

(1) Background: Poly(lactic-co-glycolic acid) (PLGA) nanoparticles (NPs) loaded with Tobramycin were prepared using a solvent-evaporation method. (2) Methods: The NPs were coated with low molecular weight chitosan (LMWC) to enhance the mucoadhesiveness of PLGA-NPs. The following w/w ratios of tobram...

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Detalhes bibliográficos
Publicado no:Pharmaceuticals (Basel)
Main Authors: Al-Nemrawi, Nusaiba K., Alshraiedeh, Nid’’A H., Zayed, Aref L., Altaani, Bashar M.
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5874724/
https://ncbi.nlm.nih.gov/pubmed/29517998
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ph11010028
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