Regulation of the Biosynthesis of the Macrolide Antibiotic Spiramycin in Streptomyces ambofaciens

Streptomyces ambofaciens synthesizes the macrolide antibiotic spiramycin. The biosynthetic gene cluster for spiramycin has been characterized for S. ambofaciens. In addition to the regulatory gene srmR (srm22), previously identified (M. Geistlich et al., Mol. Microbiol. 6:2019-2029, 1992), three put...

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Bibliografiske detaljer
Main Authors: Karray, Fatma, Darbon, Emmanuelle, Nguyen, Hoang Chuong, Gagnat, Josette, Pernodet, Jean-Luc
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology (ASM) 2010
Fag:
Genetics and Molecular Biology
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2953699/
https://ncbi.nlm.nih.gov/pubmed/20817767
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JB.00712-10
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