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Post-PKS Tailoring Steps of the Spiramycin Macrolactone Ring in Streptomyces ambofaciens
Spiramycins are clinically important 16-member macrolide antibiotics produced by Streptomyces ambofaciens. Biosynthetic studies have established that the earliest lactonic intermediate in spiramycin biosynthesis, the macrolactone platenolide I, is synthesized by a type I modular polyketide synthase...
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| Hoofdauteurs: | , , , , |
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| Formaat: | Artigo |
| Taal: | Inglês |
| Gepubliceerd in: |
American Society for Microbiology
2013
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| Onderwerpen: | |
| Online toegang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3719765/ https://ncbi.nlm.nih.gov/pubmed/23716060 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.00512-13 |
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