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Regulation of the Biosynthesis of the Macrolide Antibiotic Spiramycin in Streptomyces ambofaciens

Streptomyces ambofaciens synthesizes the macrolide antibiotic spiramycin. The biosynthetic gene cluster for spiramycin has been characterized for S. ambofaciens. In addition to the regulatory gene srmR (srm22), previously identified (M. Geistlich et al., Mol. Microbiol. 6:2019-2029, 1992), three put...

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Detalhes bibliográficos
Main Authors: Karray, Fatma, Darbon, Emmanuelle, Nguyen, Hoang Chuong, Gagnat, Josette, Pernodet, Jean-Luc
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 2010
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2953699/
https://ncbi.nlm.nih.gov/pubmed/20817767
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JB.00712-10
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