Regulation of the Biosynthesis of the Macrolide Antibiotic Spiramycin in Streptomyces ambofaciens

Streptomyces ambofaciens synthesizes the macrolide antibiotic spiramycin. The biosynthetic gene cluster for spiramycin has been characterized for S. ambofaciens. In addition to the regulatory gene srmR (srm22), previously identified (M. Geistlich et al., Mol. Microbiol. 6:2019-2029, 1992), three put...

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Bibliografische gegevens
Hoofdauteurs: Karray, Fatma, Darbon, Emmanuelle, Nguyen, Hoang Chuong, Gagnat, Josette, Pernodet, Jean-Luc
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: American Society for Microbiology (ASM) 2010
Onderwerpen:
Genetics and Molecular Biology
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2953699/
https://ncbi.nlm.nih.gov/pubmed/20817767
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JB.00712-10
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