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Regulation of the Biosynthesis of the Macrolide Antibiotic Spiramycin in Streptomyces ambofaciens

Streptomyces ambofaciens synthesizes the macrolide antibiotic spiramycin. The biosynthetic gene cluster for spiramycin has been characterized for S. ambofaciens. In addition to the regulatory gene srmR (srm22), previously identified (M. Geistlich et al., Mol. Microbiol. 6:2019-2029, 1992), three put...

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Autors principals: Karray, Fatma, Darbon, Emmanuelle, Nguyen, Hoang Chuong, Gagnat, Josette, Pernodet, Jean-Luc
Format: Artigo
Idioma:Inglês
Publicat: American Society for Microbiology (ASM) 2010
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2953699/
https://ncbi.nlm.nih.gov/pubmed/20817767
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JB.00712-10
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