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Individual and overlapping roles of BH3-only proteins Bim and Bad in apoptosis of lymphocytes and platelets and in suppression of thymic lymphoma development

BH3-only proteins, such as Bim and Bad, contribute to tissue homeostasis by initiating apoptosis in a cell type- and stimulus-specific manner. Loss of Bim provokes lymphocyte accumulation in vivo and renders lymphocytes more resistant to diverse apoptotic stimuli and Bad has been implicated in the a...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Kelly, PN, White, MJ, Goschnick, MW, Fairfax, KA, Tarlinton, DM, Kinkel, SA, Bouillet, P, Adams, JM, Kile, BT, Strasser, A
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: 2010
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC2953537/
https://ncbi.nlm.nih.gov/pubmed/20431598
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cdd.2010.43
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