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Proapoptotic BH3-only protein Bim is essential for developmentally programmed death of germinal center-derived memory B cells and antibody-forming cells

T cell–dependent B-cell immune responses induce germinal centers that are sites for expansion, diversification, and selection of antigen-specific B cells. During the immune response, antigen-specific B cells are removed in a process that favors the retention of cells with improved affinity for antig...

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Bibliografske podrobnosti
Main Authors: Fischer, Silke F., Bouillet, Philippe, O'Donnell, Kristy, Light, Amanda, Tarlinton, David M., Strasser, Andreas
Format: Artigo
Jezik:Inglês
Izdano: American Society of Hematology 2007
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC2190612/
https://ncbi.nlm.nih.gov/pubmed/17720882
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2007-05-091306
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