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BMI1-mediated histone ubiquitylation promotes DNA double-strand break repair
Polycomb group (PcG) proteins are major determinants of cell identity, stem cell pluripotency, and epigenetic gene silencing during development. The polycomb repressive complex 1, which contains BMI1, RING1, and RING2, functions as an E3-ubuiquitin ligase. We found that BMI1 and RING2 are recruited...
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| Hauptverfasser: | , , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
The Rockefeller University Press
2010
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2953429/ https://ncbi.nlm.nih.gov/pubmed/20921134 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.201003034 |
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