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Writers, Readers, and Erasers of Histone Ubiquitylation in DNA Double-Strand Break Repair

DNA double-strand breaks (DSBs) are highly cytotoxic DNA lesions, whose faulty repair may alter the content and organization of cellular genomes. To counteract this threat, numerous signaling and repair proteins are recruited hierarchically to the chromatin areas surrounding DSBs to facilitate accur...

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Detalhes bibliográficos
Publicado no:Front Genet
Main Authors: Smeenk, Godelieve, Mailand, Niels
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4923129/
https://ncbi.nlm.nih.gov/pubmed/27446204
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fgene.2016.00122
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