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Ultrastructural Analysis of ICP34.5(−) Herpes Simplex Virus 1 Replication in Mouse Brain Cells In Vivo
Replication-competent forms of herpes simplex virus 1 (HSV-1) defective in the viral neurovirulence factor infected cell protein 34.5 (ICP34.5) are under investigation for use in the therapeutic treatment of cancer. In mouse models, intratumoral injection of ICP34.5-defective oncolytic HSVs (oHSVs)...
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| Autori principali: | , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
American Society for Microbiology (ASM)
2010
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2953204/ https://ncbi.nlm.nih.gov/pubmed/20702618 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00337-10 |
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