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An avirulent ICP34.5 deletion mutant of herpes simplex virus type 1 is capable of in vivo spontaneous reactivation.

The herpes simplex virus type 1 (HSV-1) ICP34.5 gene is a neurovirulence gene in mice. In addition, some ICP34.5 mutants have been reported to have a reduced efficiency of induced reactivation as measured by in vitro explantation of latently infected mouse ganglia. However, since spontaneous reactiv...

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Detalhes bibliográficos
Main Authors: Perng, G C, Thompson, R L, Sawtell, N M, Taylor, W E, Slanina, S M, Ghiasi, H, Kaiwar, R, Nesburn, A B, Wechsler, S L
Formato: Artigo
Idioma:Inglês
Publicado em: 1995
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC189003/
https://ncbi.nlm.nih.gov/pubmed/7707530
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