An avirulent ICP34.5 deletion mutant of herpes simplex virus type 1 is capable of in vivo spontaneous reactivation.

The herpes simplex virus type 1 (HSV-1) ICP34.5 gene is a neurovirulence gene in mice. In addition, some ICP34.5 mutants have been reported to have a reduced efficiency of induced reactivation as measured by in vitro explantation of latently infected mouse ganglia. However, since spontaneous reactiv...

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Veröffentlicht in:	J Virol
Hauptverfasser:	Perng, G C, Thompson, R L, Sawtell, N M, Taylor, W E, Slanina, S M, Ghiasi, H, Kaiwar, R, Nesburn, A B, Wechsler, S L
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	American Society for Microbiology (ASM) 1995
Schlagworte:	Research Article
Online-Zugang:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC189003/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7707530/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.69.5.3033-3041.1995
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