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Ultrastructural Analysis of ICP34.5(−) Herpes Simplex Virus 1 Replication in Mouse Brain Cells In Vivo

Replication-competent forms of herpes simplex virus 1 (HSV-1) defective in the viral neurovirulence factor infected cell protein 34.5 (ICP34.5) are under investigation for use in the therapeutic treatment of cancer. In mouse models, intratumoral injection of ICP34.5-defective oncolytic HSVs (oHSVs)...

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Sonraí Bibleagrafaíochta
Main Authors: Mehta, Hina, Muller, Jacqueline, Markovitz, Nancy S.
Formáid: Artigo
Teanga:Inglês
Foilsithe: American Society for Microbiology (ASM) 2010
Ábhair:
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2953204/
https://ncbi.nlm.nih.gov/pubmed/20702618
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00337-10
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