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Strain-Specific Differences in the Impact of Human TRIM5α, Different TRIM5α Alleles, and the Inhibition of Capsid-Cyclophilin A Interactions on the Infectivity of HIV-1

HIV-1 infectivity is strongly restricted by TRIM5α from certain primate species but has been described as being only marginally susceptible to human TRIM5α. In this study, we evaluated the effects of the modulation of human TRIM5α activity (pretreatment of target cells with alpha interferon, express...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Battivelli, Emilie, Lecossier, Denise, Matsuoka, Saori, Migraine, Julie, Clavel, François, Hance, Allan J.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: American Society for Microbiology (ASM) 2010
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC2953162/
https://ncbi.nlm.nih.gov/pubmed/20702630
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00758-10
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