Modulation of HIV-1 infectivity and cyclophilin A-dependence by Gag sequence and target cell type

BACKGROUND: HIV-1 Gag proteins are essential for virion assembly and viral replication in newly infected cells. Gag proteins are also strong determinants of viral infectivity; immune escape mutations in the Gag capsid (CA) protein can markedly reduce viral fitness, and interactions of CA with host p...

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Bibliografiske detaljer
Main Authors: Matsuoka, Saori, Dam, Elisabeth, Lecossier, Denise, Clavel, François, Hance, Allan J
Format: Artigo
Sprog:Inglês
Udgivet: BioMed Central 2009
Fag:
Research
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2653016/
https://ncbi.nlm.nih.gov/pubmed/19254360
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1742-4690-6-21
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