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Modulation of HIV-1 infectivity and cyclophilin A-dependence by Gag sequence and target cell type
BACKGROUND: HIV-1 Gag proteins are essential for virion assembly and viral replication in newly infected cells. Gag proteins are also strong determinants of viral infectivity; immune escape mutations in the Gag capsid (CA) protein can markedly reduce viral fitness, and interactions of CA with host p...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
BioMed Central
2009
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2653016/ https://ncbi.nlm.nih.gov/pubmed/19254360 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1742-4690-6-21 |
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