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Modulation of TRIM5α Activity in Human Cells by Alternatively Spliced TRIM5 Isoforms
TRIM5α is a restriction factor that can block an early step in the retroviral life cycle by recognizing and causing the disassembly of incoming viral capsids, thereby preventing the completion of reverse transcription. Numerous other isoforms of human TRIM5 exist, and isoforms lacking a C-terminal S...
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| Autors principals: | , , , , , , , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
American Society for Microbiology
2011
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3147942/ https://ncbi.nlm.nih.gov/pubmed/21632761 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00648-11 |
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