Pressure from TRIM5α Contributes to Control of HIV-1 Replication by Individuals Expressing Protective HLA-B Alleles

The expression of certain HLA class I alleles, including HLA-B*27 and HLA-B*57, is associated with better control of human immunodeficiency virus type 1 (HIV-1) infection, but the mechanisms responsible are not fully understood. We sought evidence that pressure from the human restriction factor TRIM...

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Autores principales: Granier, Clémence, Battivelli, Emilie, Lécuroux, Camille, Venet, Alain, Lambotte, Olivier, Schmitt-Boulanger, Marion, Delaugerre, Constance, Molina, Jean-Michel, Chakrabarti, Lisa A., Clavel, François, Hance, Allan J.
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Microbiology 2013
Materias:
Pathogenesis and Immunity
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3753996/
https://ncbi.nlm.nih.gov/pubmed/23864638
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01313-13
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