Llwytho...

Glycosaminoglycan-binding properties and kinetic characterization of human heparin cofactor II expressed in Escherichia coli

Irreversible inactivation of α-thrombin (T) by the serpin, heparin cofactor II (HCII), is accelerated by ternary complex formation with the glycosaminoglycans (GAGs) heparin and dermatan sulfate (DS). Low expression of human HCII in Escherichia coli was optimized by silent mutation of 27 rare codons...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Sarilla, Suryakala, Habib, Sally Y., Tollefsen, Douglas M., Friedman, David B., Arnett, Diana R., Verhamme, Ingrid M.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: 2010
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC2952836/
https://ncbi.nlm.nih.gov/pubmed/20670608
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ab.2010.07.024
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