Anti-apoptotic Protein BCL2 Down-regulates DNA End Joining in Cancer Cells

Cancer cells are often associated with secondary chromosomal rearrangements, such as deletions, inversions, and translocations, which could be the consequence of unrepaired/misrepaired DNA double strand breaks (DSBs). Nonhomologous DNA end joining is one of the most common pathways to repair DSBs in...

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Detaylı Bibliyografya
Asıl Yazarlar: Kumar, Tadi Satish, Kari, Vijayalakshmi, Choudhary, Bibha, Nambiar, Mridula, Akila, T. S., Raghavan, Sathees C.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: American Society for Biochemistry and Molecular Biology 2010
Konular:
DNA and Chromosomes
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC2952268/
https://ncbi.nlm.nih.gov/pubmed/20699221
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M110.140350
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