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SCR7, a potent cancer therapeutic agent and a biochemical inhibitor of nonhomologous DNA end‐joining

BACKGROUND: DNA double‐strand breaks (DSBs) are harmful to the cell as it could lead to genomic instability and cell death when left unrepaired. Homologous recombination and nonhomologous end‐joining (NHEJ) are two major DSB repair pathways, responsible for ensuring genome integrity in mammals. Ther...

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Detalhes bibliográficos
Publicado no:Cancer Rep (Hoboken)
Main Authors: Manjunath, Meghana, Choudhary, Bibha, Raghavan, Sathees C.
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2021
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8222562/
https://ncbi.nlm.nih.gov/pubmed/33496064
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/cnr2.1341
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