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SCR7, a potent cancer therapeutic agent and a biochemical inhibitor of nonhomologous DNA end‐joining

BACKGROUND: DNA double‐strand breaks (DSBs) are harmful to the cell as it could lead to genomic instability and cell death when left unrepaired. Homologous recombination and nonhomologous end‐joining (NHEJ) are two major DSB repair pathways, responsible for ensuring genome integrity in mammals. Ther...

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Bibliographische Detailangaben
Veröffentlicht in:Cancer Rep (Hoboken)
Hauptverfasser: Manjunath, Meghana, Choudhary, Bibha, Raghavan, Sathees C.
Format: Artigo
Sprache:Inglês
Veröffentlicht: John Wiley and Sons Inc. 2021
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC8222562/
https://ncbi.nlm.nih.gov/pubmed/33496064
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/cnr2.1341
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