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DNA repair of myeloma plasma cells correlates with clinical outcome: the effect of the nonhomologous end-joining inhibitor SCR7

DNA repair activity of malignant cells seems to influence therapeutic outcome and patients’ survival. Herein, we investigated the mechanistic basis for the link between DNA repair efficiency and response to antimyeloma therapy. Nucleotide excision repair (NER), interstrand cross-links repair (ICL/R)...

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Detalhes bibliográficos
Publicado no:Blood
Main Authors: Gkotzamanidou, Maria, Terpos, Evangelos, Bamia, Christina, Munshi, Nikhil C., Dimopoulos, Meletios A., Souliotis, Vassilis L.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society of Hematology 2016
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5524533/
https://ncbi.nlm.nih.gov/pubmed/27443291
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2016-01-691618
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