DNA repair of myeloma plasma cells correlates with clinical outcome: the effect of the nonhomologous end-joining inhibitor SCR7

DNA repair activity of malignant cells seems to influence therapeutic outcome and patients’ survival. Herein, we investigated the mechanistic basis for the link between DNA repair efficiency and response to antimyeloma therapy. Nucleotide excision repair (NER), interstrand cross-links repair (ICL/R)...

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Bibliographische Detailangaben
Veröffentlicht in:Blood
Hauptverfasser: Gkotzamanidou, Maria, Terpos, Evangelos, Bamia, Christina, Munshi, Nikhil C., Dimopoulos, Meletios A., Souliotis, Vassilis L.
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society of Hematology 2016
Schlagworte:
Lymphoid Neoplasia
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5524533/
https://ncbi.nlm.nih.gov/pubmed/27443291
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2016-01-691618
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