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DNA repair of myeloma plasma cells correlates with clinical outcome: the effect of the nonhomologous end-joining inhibitor SCR7

DNA repair activity of malignant cells seems to influence therapeutic outcome and patients’ survival. Herein, we investigated the mechanistic basis for the link between DNA repair efficiency and response to antimyeloma therapy. Nucleotide excision repair (NER), interstrand cross-links repair (ICL/R)...

詳細記述

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書誌詳細
出版年:Blood
主要な著者: Gkotzamanidou, Maria, Terpos, Evangelos, Bamia, Christina, Munshi, Nikhil C., Dimopoulos, Meletios A., Souliotis, Vassilis L.
フォーマット: Artigo
言語:Inglês
出版事項: American Society of Hematology 2016
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC5524533/
https://ncbi.nlm.nih.gov/pubmed/27443291
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2016-01-691618
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