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DNA repair of myeloma plasma cells correlates with clinical outcome: the effect of the nonhomologous end-joining inhibitor SCR7

DNA repair activity of malignant cells seems to influence therapeutic outcome and patients’ survival. Herein, we investigated the mechanistic basis for the link between DNA repair efficiency and response to antimyeloma therapy. Nucleotide excision repair (NER), interstrand cross-links repair (ICL/R)...

पूर्ण विवरण

में बचाया:
ग्रंथसूची विवरण
में प्रकाशित:Blood
मुख्य लेखकों: Gkotzamanidou, Maria, Terpos, Evangelos, Bamia, Christina, Munshi, Nikhil C., Dimopoulos, Meletios A., Souliotis, Vassilis L.
स्वरूप: Artigo
भाषा:Inglês
प्रकाशित: American Society of Hematology 2016
विषय:
ऑनलाइन पहुंच:https://ncbi.nlm.nih.gov/pmc/articles/PMC5524533/
https://ncbi.nlm.nih.gov/pubmed/27443291
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2016-01-691618
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