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Anti-apoptotic Protein BCL2 Down-regulates DNA End Joining in Cancer Cells
Cancer cells are often associated with secondary chromosomal rearrangements, such as deletions, inversions, and translocations, which could be the consequence of unrepaired/misrepaired DNA double strand breaks (DSBs). Nonhomologous DNA end joining is one of the most common pathways to repair DSBs in...
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| Главные авторы: | , , , , , |
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| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
American Society for Biochemistry and Molecular Biology
2010
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2952268/ https://ncbi.nlm.nih.gov/pubmed/20699221 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M110.140350 |
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