Cryptochrome Mediates Circadian Regulation of cAMP Signaling and Hepatic Gluconeogenesis

During fasting, mammals maintain glucose homeostasis by stimulating hepatic gluconeogenesis1. Elevations in circulating glucagon (GLU) and epinephrine trigger the cAMP mediated phosphorylation of Creb and dephosphorylation of the Creb coactivator Crtc22. Although the underlying mechanism is unclear,...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Zhang, Eric E., Liu, Yi, Dentin, Renaud, Pongsawakul, Pagkapol Y., Liu, Andrew C., Hirota, Tsuyoshi, Nusinow, Dmitri A., Sun, Xiujie, Landais, Severine, Kodama, Yuzo, Brenner, David A., Montminy, Marc, Kay, Steve A.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: 2010
Gaiak:
Article
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC2952072/
https://ncbi.nlm.nih.gov/pubmed/20852621
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nm.2214
Etiketak: Etiketa erantsi
Etiketarik gabe, Izan zaitez lehena erregistro honi etiketa jartzen!

Antzeko izenburuak