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In Vivo Role of Phosphorylation of Cryptochrome 2 in the Mouse Circadian Clock

The circadian clock is finely regulated by posttranslational modifications of clock components. Mouse CRY2, a critical player in the mammalian clock, is phosphorylated at Ser557 for proteasome-mediated degradation, but its in vivo role in circadian organization was not revealed. Here, we generated C...

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Bibliografske podrobnosti
izdano v:Mol Cell Biol
Main Authors: Hirano, Arisa, Kurabayashi, Nobuhiro, Nakagawa, Tomoki, Shioi, Go, Todo, Takeshi, Hirota, Tsuyoshi, Fukada, Yoshitaka
Format: Artigo
Jezik:Inglês
Izdano: American Society for Microbiology 2014
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4248739/
https://ncbi.nlm.nih.gov/pubmed/25288642
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.00711-14
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