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FAD regulates CRYPTOCHROME protein stability and circadian clock in mice
The circadian clock generates biological rhythms of metabolic and physiological processes, including the sleep-wake cycle. We previously identified a missense mutation in the flavin adenine dinucleotide (FAD) binding pocket of CRYPTOCHROME2 (CRY2), a clock protein that causes human advanced sleep ph...
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| Publié dans: | Cell Rep |
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| Auteurs principaux: | , , , |
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
2017
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5423466/ https://ncbi.nlm.nih.gov/pubmed/28402850 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2017.03.041 |
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