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FAD regulates CRYPTOCHROME protein stability and circadian clock in mice

The circadian clock generates biological rhythms of metabolic and physiological processes, including the sleep-wake cycle. We previously identified a missense mutation in the flavin adenine dinucleotide (FAD) binding pocket of CRYPTOCHROME2 (CRY2), a clock protein that causes human advanced sleep ph...

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發表在:Cell Rep
Main Authors: Hirano, Arisa, Braas, Daniel, Fu, Ying-Hui, Ptáček, Louis J.
格式: Artigo
語言:Inglês
出版: 2017
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC5423466/
https://ncbi.nlm.nih.gov/pubmed/28402850
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2017.03.041
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