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Cells navigate with a local-excitation, global-inhibition-biased excitable network

Cells have an internal compass that enables them to move along shallow chemical gradients. As amoeboid cells migrate, signaling events such as Ras and PI3K activation occur spontaneously on pseudopodia. Uniform stimuli trigger a symmetric response, whereupon cells stop and round up; then localized p...

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Detalhes bibliográficos
Main Authors: Xiong, Yuan, Huang, Chuan-Hsiang, Iglesias, Pablo A., Devreotes, Peter N.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2951443/
https://ncbi.nlm.nih.gov/pubmed/20864631
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1011271107
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