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Evolutionarily Conserved Coupling of Adaptive and Excitable Networks Mediates Eukaryotic Chemotaxis

Numerous models explain how cells sense and migrate toward shallow chemoattractant gradients. Studies show that an excitable signal transduction network acts as a pacemaker that controls the cytoskeleton to drive motility. Here we show that this network is required to link stimuli to actin polymeriz...

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Bibliografische gegevens
Hoofdauteurs: Tang, Ming, Wang, Mingjie, Shi, Changji, Iglesias, Pablo A., Devreotes, Peter N., Huang, Chuan-Hsiang
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2014
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4211273/
https://ncbi.nlm.nih.gov/pubmed/25346418
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms6175
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