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An Excitable Signal Integrator Couples to an Idling Cytoskeletal Oscillator to Drive Cell Migration

It is generally believed that cytoskeletal activities drive random cell migration while signal transduction events initiated by receptors regulate the cytoskeleton to guide cells. However, we find that the cytoskeletal network, involving Scar/Wave, Arp 2/3, and actin binding proteins, is only capabl...

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Detalhes bibliográficos
Main Authors: Huang, Chuan-Hsiang, Tang, Ming, Shi, Changji, Iglesias, Pablo A., Devreotes, Peter N.
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3838899/
https://ncbi.nlm.nih.gov/pubmed/24142103
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncb2859
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