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Evolutionarily Conserved Coupling of Adaptive and Excitable Networks Mediates Eukaryotic Chemotaxis

Numerous models explain how cells sense and migrate toward shallow chemoattractant gradients. Studies show that an excitable signal transduction network acts as a pacemaker that controls the cytoskeleton to drive motility. Here we show that this network is required to link stimuli to actin polymeriz...

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Main Authors: Tang, Ming, Wang, Mingjie, Shi, Changji, Iglesias, Pablo A., Devreotes, Peter N., Huang, Chuan-Hsiang
Format: Artigo
Jezik:Inglês
Izdano: 2014
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4211273/
https://ncbi.nlm.nih.gov/pubmed/25346418
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms6175
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