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Asymmetric Hydrophosphylation of Chiral N-Phosphonyl Imines Provides an Efficient Approach to Chiral α-Amino Phosphonates
Chiral N-phosphonylimines were found to react with lithium phosphites to provide various substituted chiral α-amino phosphonates in excellent yields (94–97%) and diastereoselectivities (93:7 to 99:1). The types of bases utilized for generating the nucleophile are crucial for the effectiveness of asy...
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| Main Authors: | , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2010
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2951300/ https://ncbi.nlm.nih.gov/pubmed/20887612 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1747-0285.2010.01013.x |
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