Early versus late treatment of spinal cord compression with long-term intrathecal enzyme replacement therapy in canine mucopolysaccharidosis type I

Enzyme replacement therapy (ERT) with intravenous recombinant human alpha-l-iduronidase (IV rhIDU) is a treatment for patients with mucopolysaccharidosis I (MPS I). Spinal cord compression develops in MPS I patients due in part to dural and leptomeningeal thickening from accumulated glycosaminoglyca...

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Main Authors: Dickson, Patricia I., Hanson, Stephen, McEntee, Michael F., Vite, Charles H., Vogler, Carole A., Mlikotic, Anton, Chen, Agnes H., Ponder, Katherine P., Haskins, Mark E., Tippin, Brigette L., Le, Steven Q., Passage, Merry B., Guerra, Catalina, Dierenfeld, Ashley, Jens, Jackie, Snella, Elizabeth, Kan, Shih-hsin, Ellinwood, N. Matthew
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2950221/
https://ncbi.nlm.nih.gov/pubmed/20655780
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ymgme.2010.06.020
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