Early versus late treatment of spinal cord compression with long-term intrathecal enzyme replacement therapy in canine mucopolysaccharidosis type I

Enzyme replacement therapy (ERT) with intravenous recombinant human alpha-l-iduronidase (IV rhIDU) is a treatment for patients with mucopolysaccharidosis I (MPS I). Spinal cord compression develops in MPS I patients due in part to dural and leptomeningeal thickening from accumulated glycosaminoglyca...

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Main Authors: Dickson, Patricia I., Hanson, Stephen, McEntee, Michael F., Vite, Charles H., Vogler, Carole A., Mlikotic, Anton, Chen, Agnes H., Ponder, Katherine P., Haskins, Mark E., Tippin, Brigette L., Le, Steven Q., Passage, Merry B., Guerra, Catalina, Dierenfeld, Ashley, Jens, Jackie, Snella, Elizabeth, Kan, Shih-hsin, Ellinwood, N. Matthew
Format: Artigo
Sprog:Inglês
Udgivet: 2010
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2950221/
https://ncbi.nlm.nih.gov/pubmed/20655780
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ymgme.2010.06.020
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