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Arterial Pathology in Canine Mucopolysaccharidosis-I and Response to Therapy

Mucopolysaccharidosis-I (MPS-I) is an inherited deficiency of α-L-iduronidase (IdU) that causes lysosomal accumulation of glycosaminoglycans (GAG) in a variety of parenchymal cell types and connective tissues. The fundamental link between genetic mutation and tissue GAG accumulation is clear, but re...

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Detalhes bibliográficos
Main Authors: Lyons, Jeremiah A., Dickson, Patricia, Wall, Jonathan, Passage, Merry, Ellinwood, N. Matthew, Kakkis, Emil D., McEntee, Michael F.
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3084338/
https://ncbi.nlm.nih.gov/pubmed/21383673
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/labinvest.2011.7
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