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Successful induction of immune tolerance to enzyme replacement therapy in canine mucopolysaccharidosis I
Immune responses can interfere with the effective use of therapeutic proteins to treat genetic deficiencies and have been challenging to manage. To address this problem, we adapted and studied methods of immune tolerance used in canine organ transplantation research to soluble protein therapeutics....
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| Main Authors: | , , , , , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
National Academy of Sciences
2004
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC321766/ https://ncbi.nlm.nih.gov/pubmed/14715900 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0305480101 |
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