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Continuous infusion of enzyme replacement therapy is inferior to weekly infusions in MPS I dogs
Intravenous enzyme replacement therapy with recombinant human α-l-iduronidase (rhIDU) is used weekly to treat mucopolysaccharidosis (MPS) I. We tested continuous administration of rhIDU at two dosing levels (0.58 mg/kg/week and 2 mg/kg/week) in MPS I dogs, and compared the efficacy of continuous to...
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| Main Authors: | , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2009
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2889197/ https://ncbi.nlm.nih.gov/pubmed/19562502 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s10545-009-1198-5 |
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