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HnRNP proteins controlled by c-Myc deregulate pyruvate kinase mRNA splicing in cancer

When oxygen is abundant, quiescent cells efficiently extract energy from glucose primarily by oxidative phosphorylation, whereas under the same conditions tumour cells consume glucose more avidly, converting it to lactate. This long-observed phenomenon is known as aerobic glycolysis1, and is importa...

पूर्ण विवरण

में बचाया:
ग्रंथसूची विवरण
मुख्य लेखकों: David, Charles J., Chen, Mo, Assanah, Marcela, Canoll, Peter, Manley, James L.
स्वरूप: Artigo
भाषा:Inglês
प्रकाशित: 2009
विषय:
ऑनलाइन पहुंच:https://ncbi.nlm.nih.gov/pmc/articles/PMC2950088/
https://ncbi.nlm.nih.gov/pubmed/20010808
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nature08697
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