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HnRNP proteins controlled by c-Myc deregulate pyruvate kinase mRNA splicing in cancer

When oxygen is abundant, quiescent cells efficiently extract energy from glucose primarily by oxidative phosphorylation, whereas under the same conditions tumour cells consume glucose more avidly, converting it to lactate. This long-observed phenomenon is known as aerobic glycolysis1, and is importa...

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Detaylı Bibliyografya
Asıl Yazarlar: David, Charles J., Chen, Mo, Assanah, Marcela, Canoll, Peter, Manley, James L.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 2009
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC2950088/
https://ncbi.nlm.nih.gov/pubmed/20010808
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nature08697
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