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HnRNP proteins controlled by c-Myc deregulate pyruvate kinase mRNA splicing in cancer
When oxygen is abundant, quiescent cells efficiently extract energy from glucose primarily by oxidative phosphorylation, whereas under the same conditions tumour cells consume glucose more avidly, converting it to lactate. This long-observed phenomenon is known as aerobic glycolysis1, and is importa...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2009
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2950088/ https://ncbi.nlm.nih.gov/pubmed/20010808 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nature08697 |
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