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The role of animal models in advancing amyloid-beta immunotherapy to the clinic

The amyloid-beta (Aβ) hypothesis of Alzheimer's disease (AD) causality is now well into its third decade and is finally entering a phase of rigorous clinical testing in numerous late stage clinical trials. The use of Aβ-based animal models of AD has been essential to the discovery and/or precli...

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Autors principals: Games, Dora, Seubert, Peter
Format: Artigo
Idioma:Inglês
Publicat: BioMed Central 2010
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2949588/
https://ncbi.nlm.nih.gov/pubmed/20682084
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/alzrt46
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