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An Integrated Genetic-Genomic Approach for the Identification of Novel Cancer Loci in Mice Sensitized to c-Myc–Induced Apoptosis

Deregulated c-Myc is associated with a wide range of human cancers. In many cell types, overexpression of c-Myc potently promotes cell growth and proliferation concomitant with the induction of apoptosis. Secondary genetic events that shift this balance either by increasing growth and proliferation...

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Detalhes bibliográficos
Main Authors: Mendrysa, Susan M., Akagi, Keiko, Roayaei, Jean, Lien, Wen-Hui, Copeland, Neal G., Jenkins, Nancy A., Eisenman, Robert N.
Formato: Artigo
Idioma:Inglês
Publicado em: SAGE Publications 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2949282/
https://ncbi.nlm.nih.gov/pubmed/20927200
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1177/1947601910374875
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