Measuring drug occupancy in the absence of a reference region: the Lassen plot re-visited

Eitemau Tebyg

• A graphical method to compare the in vivo binding potential of PET radioligands in the absence of a reference region: application to [(11)C]PBR28 and [(18)F]PBR111 for TSPO imaging
  gan: Guo, Qi, et al.
  Cyhoeddwyd: (2014)
• A local-neighborhood Lassen plot filter for creating occupancy and non-displaceable binding images
  gan: de Laat, Bart, et al.
  Cyhoeddwyd: (2020)
• Prediction of repeat-dose occupancy from single-dose data: characterisation of the relationship between plasma pharmacokinetics and brain target occupancy
  gan: Abanades, Sergio, et al.
  Cyhoeddwyd: (2011)
• An evaluation of the brain distribution of [(11)C]GSK1034702, a muscarinic-1 (M(1)) positive allosteric modulator in the living human brain using positron emission tomography
  gan: Ridler, Khanum, et al.
  Cyhoeddwyd: (2014)
• Test–retest variability and reference region-based quantification of (18)F-BCPP-EF for imaging mitochondrial complex I in the human brain
  gan: Mansur, Ayla, et al.
  Cyhoeddwyd: (2020)