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Test–retest variability and reference region-based quantification of (18)F-BCPP-EF for imaging mitochondrial complex I in the human brain

Mitochondrial complex I (MC-I) is an essential regulator of brain bioenergetics and can be quantified in the brain using PET radioligand (18)F-BCPP-EF. Here we evaluate the test–retest reproducibility of (18)F-BCPP-EF in humans, and assess the use of a non-invasive quantification method (standardise...

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Detalhes bibliográficos
Publicado no:J Cereb Blood Flow Metab
Main Authors: Mansur, Ayla, Rabiner, Eugenii A, Tsukada, Hideo, Comley, Robert A, Lewis, Yvonne, Huiban, Mickael, Passchier, Jan, Gunn, Roger N
Formato: Artigo
Idioma:Inglês
Publicado em: SAGE Publications 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7983506/
https://ncbi.nlm.nih.gov/pubmed/32501157
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1177/0271678X20928149
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