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Depletion of Abundant Plasma Proteins and Limitations of Plasma Proteomics

Immunoaffinity depletion with antibodies to the top 7 or top 14 high abundance plasma proteins is used to enhance detection of lower abundance proteins in both shotgun and targeted proteomic analyses. We evaluated the effects of top 7/top 14 immunodepletion on the shotgun proteomic analysis of human...

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Detalles Bibliográficos
Main Authors: Tu, Chengjian, Rudnick, Paul A., Martinez, Misti Y., Cheek, Kristin L., Stein, Stephen E., Slebos, Robbert J. C., Liebler, Daniel C.
Formato: Artigo
Idioma:Inglês
Publicado: 2010
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2948641/
https://ncbi.nlm.nih.gov/pubmed/20677825
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/pr100646w
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